Volume I Computational Genomics: Large-scale pyrosequencing on the 454 GS FLX. Massively parallel short read sequencing using the Illumina Genome Analyzer. Single molecule real-time (SMRT) sequencing of PacBio RS systems. Algorithms for short read error correction. Accelerator-based techniques for short read error correction. Short-read mapping and alignment to reference genomics. Translational genomics via high-throughput sequencing. Graph-based approaches for de novo high-throughput genome assembly.
Optimization-based approaches for genome assembly. Parallel methods for large-scale assembly of high-throughput sequences. Algorithms for metagenomics. RNA-seq based transcriptome analysis via high-throughput sequencing. Annotation of plant genomes using RNA-seq data. Volume II Computational Systems Biology: Synthetic expression data generation for structure learning. Simulation and analysis of biochemical networks and dynamics. Graphical editing and simulation of biochemical networks.
Assessing methods for reverse engineering gene networks. Construction of gene regulatory networks. Construction and analysis of protein-protein interaction networks. Predicting protein function from protein-protein interaction networks. Analysis and comparison of biological networks. Identting and simulation of biochemical networks. Assessing methods for reverse engineering gene networks. Construction of gene regulatory networks.
Construction and analysis of protein-protein interaction networks. Predicting protein function from protein-protein interaction networks. Analysis and comparison of biological networks. Identifying building blocks of cellular interaction networks. Extracting modules from protein interaction networks. Computational methods for structure and function analysis of biological networks. Visualization of molecular interaction networks using Cytoscape. Integrated visualization of metabolic networks.
Volume III Computational Structural Biology: Algorithms for structural determination. Structure classification and comparison. Protein structure prediction. Protein dynamics. Protein interactions. Nucleic acid structure.