The Living Laboratory for Precision Medicine: Last-mile Solutions for Delivering Precision Medicine provides a comprehensive resource realizing the promise of precision medicine through a convergence of innovation and solutions across multiple domains - large population cohorts, artificial intelligence, genomics, phenomics, clinical trials, health economics and regulation exemplified by the living lab concept. The living lab is envisioned as an ecosystem for precision medicine discovery, delivery, and innovation, which can also act as a stimulus for regional economic growth. The term precision medicine has been popularized by clinical, scientific, political, financial and technological interests as the biggest innovation to revolutionize healthcare. While over the past decade a few precision medicine-based solutions have come to fruition, the transformative leap in healthcare delivery and population benefit is yet to be realized. Current focus on precision medicine primarily focuses on patient stratification which constrains it to either a single disease area, a few sub-disciplines, or using a limited set of genomic technologies. While useful, experience over the last few years indicates precision medicine needs to be considered as a complex process with multiple feedback loops requiring significant interdisciplinary collaboration and innovation. The Living Laboratory for Precision Medicine: Last-mile Solutions for Delivering Precision Medicine is the first to look at precision medicine through the lens of last-mile solutions which will make it broad in scope, practically relevant, and cutting-edge with blue-skies thinking. The book also explores the use of precision medicine to stimulate regional economic growth, through a healthier population, savings through healthcare costs avoidance, and using innovation as a driver of economic development.