Part I Vestibular Schwannoma 1 Controversies in the Natural History of Acoustic Neuromas 2 Controversies in Radiosurgery for Acoustic Neuromas: Single-Session Therapy versus Hypofractionated Therapy 3 Management of Residual Vestibular Schwannoma After Subtotal Resection: Observation, Repeat Surgery, or Radiosurgery? 4 Treatment Strategies for Small Intracanalicular Vestibular Schwannomas in Young Patients with Good Hearing Part II Meningioma 5 Transcranial Approaches Are Preferred for Certain Tuberculum and Olfactory Groove Meningiomas 6 Endoscopic Endonasal Surgery Is the Best Treatment for Certain Anterior Fossa Skull Base Meningiomas 7 Controversies in the Management of Petroclival Meningiomas 8 Does Embolization Have a Role to Play in the Treatment of Skull Base Meningiomas? 9 The Role of Radiotherapy for Atypical and Anaplastic Meningiomas 10 Emerging Chemotherapy and Targeted Therapy for Aggressive Meningiomas Part III Pituitary Adenoma 11 The Role of Transsphenoidal Surgery Following Nondiagnostic Inferior Petrosal Sinus Sampling in Cushing Syndrome 12 Pharmacotherapy Options After Failed Surgery for Cushing Disease 13 Primary Medical Therapy for Acromegaly, Ready for Prime Time? 14 The Role of Radiosurgery for Pituitary Adenomas 15 Exploration of the Cavernous Sinus Is Effective During Transsphenoidal Surgery for Pituitary Adenoma 16 Surgery versus Medical Management: First-Line Treatment for Pituitary Apoplexy 17 Alternative Treatment Strategies for Atypical and Aggressive Pituitary Adenomas Part IV Craniopharyngioma 18 Controversies in Radical Resection versus Subtotal Resection with Radiation in Craniopharyngioma 19 The Role of Open and Endoscopic Approaches to Craniopharyngiomas 20 The Molecular Pathogenesis of Craniopharyngioma and Potential Therapeutic Targets 21 Resection versus Cyst Fenestration: The Best Treatment for Rathke Cleft Cysts Part V Rathke Cleft Cyst and Other Sellar Lesions 22 Headache in Patients with Rathke Cleft Cysts 23 Rathke Cleft Cyst Surgery: Indications, Outcomes, and Complications 24 Controversies in the Management of Histiocytosis and Xanthogranulomas 25 Surgical Approach Selection for Skull Base Chordoma Part VI Other Cranial Tumors 26 Chordoma Genetics and Tumor Phenotype Profiles 27 Surgery versus Radiation versus Observation: What Treatment Is Best for Skull Base Paraganglioma 28 Management of Chondrosarcoma of the Cranial Base 29 Natural History and Treatment Strategies for Posterior Fossa Epidermoids 30 Indications for and Outcomes of Radiosurgery in Trigeminal and Jugular Foramen Schwannomas Part VII Cranial Nerve Schwannoma 31 Challenges of Applying Endoscopic Techniques for Cranial Nerve Schwannomas 32 Management of Cranial Nerve III, IV, and VI Schwannomas 33 Treatment of Facial Pain in Patients with Trigeminal Schwannoma 34 Induction Therapy for Esthesioneuroblastoma Part VIII Sinonasal Malignancies 35 Surgical Approach for Esthesioneuroblastoma: Controversy in Approach Selection 36 What Is the Role of Surgery for Adenoid Cystic Carcinoma 37 Proton-Beam versus Photon Therapy for Sinonasal Malignancies: Pros and Cons of Each Method 38 Controversies in Skull Base Reconstruction Techniques Part IX Surgical Approaches and Techniques 39 The Role of Lumbar Drains in Skull Base Surgery 40 The Role of Postoperative Antibiotics in Endoscopic Endonasal Surgery 41 Does Otorhinolaryngology Collaboration Improve Outcomes in Endonasal Skull Base Surgery? 42 Controversies in Outcome Measures of Skull Base Surgery 43 To Bypass or Not? The Role of Revascularization in Skull Base Surgery 44 Transcranial versus Endoscopic Repair of Lateral Sphenoid Recess Encephaloceles 45 Cranioplasty Techniques 46 The Future of Robotics in Skull Base Surgery.