Dr. Avraham Mayevsky is a Professor Emeritus in The Mina & Everard Goodman Faculty of Life Sciences and the Leslie and Susan Gonda Multidisciplinary Brain Research Center at Bar-Ilan University in Ramat-Gan, Israel. Dr Avraham Mayevsky's field of research since he started his Post-Doc training with Prof. Britton Chance in 1972, was Body Energy metabolism, including mitochondrial function in vivo, of the brain mainly and other tissues In Vivo, exposed to various pathophysiological conditions. During the 50 years of activity he and his team were able to accomplish a large number of goals that have a very significant impact on the understanding of pathophysiological processes in the brain and other organs evaluated under In Vivo conditions. His vision was to develop experimental approaches and tools that will enable them to study various physiological processes in experimental animals and at the same time, will be ready for clinical applications. During the years Dr Mayevsky's laboratory published more than 60 papers dealing with the subject of Cortical Spreading Depression of Leao (CSD).