Colin Chalk graduated from McGill University (MD,CM 1984), trained in neurology at Mayo Clinic and Oxford University, and completed a fellowship in peripheral nerve diseases at Mayo Clinic. He returned to McGill in 1991. From 2004 to 2019 he was the Director of the Division of Neurology, Montréal General Hospital. He runs peripheral neuropathy and myasthenia gravis clinics at the Montréal General Hospital, and is in charge of the Montréal General's EMG laboratory. He also has a major administrative and teaching role in the McGill Faculty of Medicine's undergraduate medical curriculum. His scholarly work in neuromuscular disease includes several Cochrane reviews, participation in multicentre clinical trials, and papers on clinical aspects of neuromuscular disease.