Already regarded as a standard reference for anyone who needs to know about the actions and uses of anti-inflammatory and analgesic drugs, this second edition provides even more. It updates information on the medicinal chemistry and the pharmaceutics of ibuprofen and its pharmacokinetics in both humans and animals. It includes molecular pharmacology and toxicological studies, and discusses the safety and efficacy of non-prescription ibuprofen, including its side effects. The text also addresses the therapeutic role of ibuprofen in rheumatic conditions, Alzheimer's disease, and cancer.