Clinicopathologic Overview of Melanoma.- Revisiting Epidermal Melanocytes: Regulation of Their Survival, Proliferation, and Function in Human Skin.- Melanoma Epidemiology.- Melanoma Genetics and Genomics.- Transcriptional Regulation in Melanoma.- MiRNAs in Malignant Melanoma.- Altered Signal Transduction Pathways in Melanoma.- Proteases in Melanoma.

- Cell-cell contacts in melanoma and the tumor microenvironment.- Regulation of Apoptosis in Melanoma Cells: Critical Targets for Therapeutic Strategies.- Senescence.- Melanoma Stem Cells.- The Birth of Malignancy: Embryogenesis and Melanoma.- Tumor Microenvironment for Melanoma Cells.- Melanoma Model Systems.- New Approaches to Signaling.

- Immune checkpoint inhibitors in melanoma define a new area in immunotherapy aiming for cure.