List of Teaching Cases xi Preface xiii Acknowledgments xv 1 Introduction 1 Section 1: Cutaneous NK/TCell lymphomas 2 The ''''parapsoriases'''': A Riddle, Wrapped in a Mystery, Inside an Enigma 15 3 Mycosis Fungoides 23 4 Sézary Syndrome 113 5 Primary Cutaneous CD30+ Lymphoproliferative Disorders 133 Lymphomatoid Papulosis 134 Cutaneous Anaplastic Large Cell Lymphoma 150 "Borderline" Cases 167 Intralymphatic CD30+ Large TCell Lymphoma 168 ImplantAssociated Anaplastic Large Cell Lymphoma 170 6 Subcutaneous Panniculitislike Tcell Lymphoma 180 7 Aggressive Cutaneous Cytotoxic Lymphomas 195 Primary Cutaneous Aggressive Epidermotropic CD8+ Cytotoxic TCell Lymphoma 196 Primary Cutaneous γ/δ TCell Lymphoma 201 Cutaneous Extranodal NK/TCell Lymphoma, Nasal Type 208 8 Cutaneous Peripheral Tcell Lymphoma, Not Otherwise Specified (NOS) 219 9 Cutaneous CD4+ Small/Medium Tcell Lymphoproliferative Disorder 228 10 Acral CD8+ Cutaneous Tcell Lymphoma 235 11 Cutaneous Adult Tcell Leukemia/Lymphoma 239 12 Other Cutaneous NK/Tcell Lymphomas 243 Cutaneous Angioimmunoblastic TCell Lymphoma 243 Hydroa VacciniformeLike Lymphoproliferative Disorder 246 Severe Mosquito Bite Allergy 250 Section 2: Cutaneous BCell lymphomas 13 Cutaneous Follicle Center Lymphoma 255 14 Cutaneous Marginal Zone Lymphoma (Cutaneous MALT Lymphoma) and Variants 274 Cutaneous Marginal Zone Lymphoma, Conventional Variant 276 Cutaneous Marginal Zone Lymphoma, Lymphoplasmacytic Variant 287 Cutaneous Marginal Zone Lymphoma, Plasmacytic Variant 290 Cutaneous Marginal Zone Lymphoma, Blastoid Variant 292 Cutaneous Amyloidoma 293 15 Cutaneous Diffuse Large Bcell Lymphoma, Leg Type 299 16 Intravascular Large Cell Lymphomas 315 Intravascular Large BCell Lymphoma 316 Intravascular Large NK/TCell Lymphoma 321 17 Other Cutaneous Bcell Lymphomas 326 Epstein-Barr Virus (EBV)Positive Cutaneous Diffuse Large BCell Lymphoma, Not Otherwise Specified (NOS) 326 Specific Cutaneous Manifestations in Mantle Cell Lymphoma 329 Specific Cutaneous Manifestations in Extracavitary Primary Effusion Lymphoma 331 Specific Cutaneous Manifestations in Multiple Myeloma 334 Specific Cutaneous Manifestations in Burkitt Lymphoma 336 Cutaneous Lymphomatoid Granulomatosis 340 Cutaneous Plasmablastic Lymphoma 342 Cutaneous TCell/HistiocyteRich Large BCell Lymphoma 344 Cutaneous Manifestations in Waldenstrom Macroglobulinemia 346 Epstein-Barr Virus (EBV)Associated Mucocutaneous Ulcers 347 Section 3: Cutaneous lymphomas in immunosuppressed individuals 18 Cutaneous Lymphomas in Immunosuppressed Individuals 357 Cutaneous Posttransplant Lymphoproliferative Disorders 358 Cutaneous Lymphomas in HIVInfected Individuals 365 Cutaneous Lymphoproliferative Disorders in Other Iatrogenic and NonIatrogenic Immune Deficiencies 368 Section 4: Specific cutaneous manifestations of leukemias and of precursor hematologic neoplasms 19 Cutaneous Manifestations of Bcell Chronic Lymphocytic Leukemia 379 Progression to Diffuse Large BCell Lymphoma (Richter Syndrome) 385 20 Cutaneous Manifestations of Myelogenous Leukemia 390 Chronic Myeloid Leukemia 399 Myelodysplastic Syndromes 400 21 Blastic Plasmacytoid Dendritic Cell Neoplasm 407 Mature Plasmacytoid Dendritic Cell Proliferations Associated With Myeloid Neoplasms 415 22 Cutaneous Manifestations of Other Leukemias 419 TCell Prolymphocytic Leukemia 419 Aggressive Natural Killer Cell Leukemia 421 Specific Skin Manifestations of Other Types of Leukemia 422 23 Cutaneous Lymphoblastic Lymphomas 424 Cutaneous BLymphoblastic Lymphoma 424 Cutaneous TLymphoblastic Lymphoma 428 Section 5: Cutaneous manifestations of other lymphomas and nonneoplastic cutaneous signs of systemic lymphomas 24 Cutaneous Manifestations of Hodgkin Lymphoma 437 Primary Cutaneous Hodgkin Lymphoma 440 25 Cutaneous Composite Lymphomas 443 26 Nonneoplastic Cutaneous Signs of Systemic Lymphomas 450 Section 6: Cutaneous lymphomas in children and adolescents 27 Cutaneous Lymphomas in Children and Adolescents 463 Mycosis Fungoides 463 Sézary Syndrome 464 Lymphomatoid Papulosis 467 Cutaneous Anaplastic Large Cell Lymphoma 467 Subcutaneous PanniculitisLike TCell Lymphoma 468 Primary Cutaneous Aggressive Epidermotropic CD8+ Cytotoxic TCell Lymphoma 468 Primary Cutaneous γ/δ TCell Lymphoma 468 Extranodal NK/TCell Lymphoma, Nasal Type 468 Primary Cutaneous Peripheral TCell Lymphoma, not Otherwise Specified (NOS) 468 Cutaneous CD4+ Small/Medium TCell Lymphoproliferative Disorder 468 Cutaneous Angioimmunoblastic TCell Lymphoma 468 Epstein-Barr Virus (EBV)Positive TCell and NKCell Lymphoproliferative Diseases of Childhood (Hydroa VacciniformeLike Lymphoproliferative Disorder, Severe Mosquito Bite Allergy) 468 Adult TCell Lymphoma/Leukemia 469 Acral CD8+ TCell Lymphoma 469 Cutaneous Follicle Center Lymphoma 469 Cutaneous Marginal Zone Lymphoma (Cutaneous MALT Lymphoma) 469 Cutaneous Burkitt Lymphoma 469 Cutaneous Intravascular Large Cell Lymphoma 469 Cutaneous Lymphomatoid Granulomatosis 469 EBV+ Mucocutaneous Ulcer 469 Cutaneous Lymphomas in Immunosuppressed Children and Adolescents 469 Cutaneous Manifestations of Myelogenous Leukemia 469 Blastic Plasmacytoid Dendritic Cell Neoplasm 470 Cutaneous Lymphoblastic Lymphoma (B or T Cell) 470 Section 7: Pseudolymphomas of the skin 28 Pseudolymphomas of the Skin 475 Chronic Actinic Dermatitis (Actinic Reticuloid) 477 Lymphomatoid Contact Dermatitis 478 Nonmycosis Fungoidesassociated Follicular Mucinosis and Other Mimickers of Pilotropic Mycosis Fungoides 479 Solitary Idiopathic B/Tcell Pseudolymphoma 481 Lichenoid (Lymphomatoid) Keratosis 483 TcellRich Angiomatoid Polypoid Pseudolymphoma/ Acral Pseudolymphomatous Angiokeratoma in Children/ Pretibial Lymphoplasmacytic Plaque in Children ("T/Bcell Angiomatoid Pseudolymphoma") 486 Lichen Aureus/Lichenoid Pigmented Purpuric Dermatitis 487 Lichen Sclerosus 489 Vitiligo 489 Annular Lichenoid Dermatitis of Youth 490 Pseudolymphomatous Acrodermatitis Chronica Atrophicans 493 Pseudolymphomatous Atopic Dermatitis 495 Nonneoplastic Erythroderma in Adult Patients 496 Pseudolymphomatous Cutaneous Infiltrates in Human Immunodeficiency Virus (HIV)Infected Patients and in Other Immune Deficiencies 499 CD30+ Tcell Pseudolymphomas 502 Persistent Nodular Arthropod Bite Reactions and Nodular Scabies 502 Pseudolymphomas in Herpes Simplex and Herpes Zoster Infections 504 Hydroa Vacciniforme 506 Pityriasis Lichenoides 507 Pseudolymphomas Associated with Lupus Erythematosus 511 Lymphomatoid Drug Reactions 515 Lymphocytoma Cutis 516 Lymphocytoma Cutis Associated with Borrelia Infection 518 Pseudolymphomas at Sites of Vaccination 522 Pseudolymphomas in Tattoos 524 Localized Scleroderma/Morphea 524 Cutaneous IgG4Related Disease 526 Pseudolymphomas in Syphilis 529 Cutaneous Plasma Cell Granuloma 534 Cutaneous and Systemic Plasmacytosis 535 Cutaneous Manifestations of Castleman Disease 536 Cutaneous Extramedullary Hematopoiesis 537 Histiocytoid Sweet Syndrome 538 Intralymphatic Histiocytosis 539 Benign Intralymphatic Proliferation of Tcell Lymphoid Blasts 541 Other "Accidental" Pseudolymphomas 543 "Malignant" Pseudolymphomas 546 Section 8: The cutaneous "atypical lymphoid proliferation" 29 The Cutaneous "Atypical Lymphoid Proliferation" 565 Index 569.