The need for neuropathology reviews in epilepsy surgery tissues steadily increases. However, textbooks and case presentations highlighting and focusing on this specific topic are rare. The authors of this book reviewed their professional experience in surgical and post-mortem europathology studies to compile a coherent summary of clinico-pathological findings, current classification schemes, useful protocols and research data for major histopathological entities of brain lesions encountered in modern epilepsy surgery programs, which is hippocampal sclerosis, brain tumours associated with early epilepsy onset, malformations of cortical development, brain inflammation and malformative vascular lesions. They did not intend to be exhaustive but rather representative of the main lesions and pathologies encountered. Thirty-two illustrated cases constitute the core of this book and will be very helpful in current practice.