Section I: Cancer treatment and challenges 1: New developments in treatment of cancer 2: A summary of molecular pathways responsible for cancer progression 3: Challenges in treatment of cancer with conventional strategies Section II: Phytochemicals and cancer therapy 4: Phytochemicals in suppressing cancer proliferation 5: Phytochemicals in suppressing cancer metastasis 6: Phytochemicals in providing cancer therapy sensitivity Section III: Phytochemicals in the treatment of other diseases 7: Phytochemicals in treatment of Diabetes mellitus 8: Phytochemicals in treatment of neurological diseases 9: Phytochemicals in treatment of ischemic/reperfusion injury 10: Phytochemicals in treatment of infectious diseases Section IV: Phytochemicals and cellular mechanisms in cancer therapy 11: Phytochemicals in regulating glycolysis in cancer 12: Phytochemicals in regulating apoptosis in cancer 13: Phytochemicals in regulating autophagy in cancer 14: Phytochemicals in regulating EMT and MMPs in cancer Section V: Phytochemicals and molecular pathways in cancer 15: Phytochemicals in regulating STAT3 signaling in cancer 16: Phytochemicals in regulating Wnt signaling in cancer 17: Phytochemicals in regulating NF-kB signaling signaling in cancer 18: Phytochemicals in regulating PTEN/PI3K/Akt signaling in cancer 19: Phytochemicals in regulating non-coding RNAs in cancer Section VI: Nano-scale delivery systems for phytochemicals in cancer therapy 20: Polymeric nanoparticles for delivery of phytochemicals in cancer therapy 21: Lipid-based nanoparticles for delivery of phytochemicals in cancer therapy 22: Carbon- and metal-based nanomaterials for delivery of phytochemicals in cancer therapy Section VII: Clinical applications 23: Application of phytochemicals in clinical trials for treatment of diseases and malignant tumors 24: The market of natural products around the world.