Section1-introduction to the basics of stem cell transplant and t cells.- history of stem cell transplant.- basics of stem cell transplant.- hematopoiesis.- t cell development-1.- t cell development-2.- role of thymus.- immunology of stem cell transplant.
- early t precursor cell.- regulatory t cells.- tolerance induction.- section 2: b cells and dendritic cells.- b cells.- dendritic cells.- section 3: diseases of t cells.- t cell malignancies.
- primary immunodeficiency diseases.- section 4: pre-transplant procedures.- apheresis.- cryopreservation.- section 5: radio-chemotherapeutic agents used in stem cell transplant.- classification of conditioning regimens.- chemotherapeutic agents used in stem cell transplant.- role of anti-thymocyte globulin in stem cell transplant.
- total body irradiation.- section 6: autologous stem cell transplant.- indications for autologous stem cell transplant.- stem cell transplant for autoimmune diseases.- stem cell transplant for hodgkin lymphoma.- stem cell transplant for b cell non-hodgkin lymphoma.- stem cell transplant for t cell non-hodgkin lymphoma.- stem cell transplant for plasma cell dyscrasias.
- section 7: allogeneic stem cell transplant.- indications allogeneic stem cell transplant.- stem cell transplant for severe aplastic anemia.- stem cell transplant for hemoglobinopathies.- stem cell transplant for acute lymphoblastic leukemia.- stem cell transplant for acute myeloblastic leukemia.- stem cell transplant for myelofibrosis.- section 8: haploidentical stem cell transplant.
- haploidentical stem cell transplant.- section 9: graft-versus-host disease.- acute gvhd.- chronic gvhd.- section10: post transplant monitoring and management.- immune reconstitution following stem cell transplant.- drugs used post stem cell transplant.- chimerism post stem cell transplant.
- post transplant immunosuppression.- donor lymphocyte infusion.- adoptive t cell therapy.- section 11: infections post stem cell transplant.- bacterial infections poststem cell transplant.- clostridium difficile infection in stem cell transplant recipients.- cytomegalovirus infection post stem cell transplant.- fungal infections post stem cell transplant.
- viral infections in patients undergoing chemotherapy and stem cell transplant.- pneumocystis jirovecii in patients undergoing chemotherapy and stem cell transplant.- section 12: complications post stem cell transplant.- complications in patients post stem cell transplant.- engraftment syndrome post stem cell transplant.- hemorrhagic cystitis post stem cell transplant.- sinusoidal obstruction syndrome in patients post stem cell transplant.- relapse following allogeneic stem cell transplant.
- abo mismatched stem cell transplant and related complications.- cytopenias post stem cell transplant.- section 13: miscellaneous.- pre-transplant evaluation.- major histocompatibility complex.- vaccination post stem cell transplant.- hemophagocytic lymphohistiocytosis.- electrolyte management during stem cell transplant.
- miscellaneous questions.