In this issue of Oral and Maxillofacial Surgery Clinics, guest editors Drs. Neel Bhattacharyya and Donald Cohen bring their considerable expertise to the topic of Diagnosis and Management of Oral Mucosal Lesions. Top experts in the field review a host of common oral mucosal lesions from a wide variety of causes, including oral manifestations of systemic diseases, vesiculobullous diseases, and pigmented lesions-all with an emphasis on new important entities, clinical pearls for diagnosis, and effective and newer treatments. Contains 11 practice-oriented topics including fungal lesions of the oral mucosa; bacterial lesions of the oral mucosa; oral lesions associated with systemic disease; autoimmune lesions of the oral mucosa; pigmented lesions of the oral cavity; and more. Provides in-depth clinical reviews on diagnosis and management of oral mucosal lesions, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.