Reactive oxygen (ROS), nitrogen (RNS), and sulfur (RSS) species are implicated in the pathogenesis of a variety of pathological conditions, including chronic infections, inflammatory disorders, cardiovascular diseases, neurodegenerative diseases, and cancer. Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects is edited by a stellar team of active researchers. The book explores the field using an interdisciplinary approach, including chemical, biological, physiological, pharmaceutical, pharmacological, and physicochemical perspectives. The book is comprised of three main parts. The first one discusses the biochemical aspects of oxidative stress modulation. It opens with an introduction to the field by the Editors, followed by chapter two covering antioxidants as modulators against proteinopathies, chapter three on cutaneous physiological redox, and chapter four on ferroptosis and metabolism. Part two - physiological and pathophysiological aspects include a collection of chapters on relevant conditions, including aging, neurological diseases, cerebral cavernous malformation, maternal and early-life malnutrition, Alzheimer's disease, liver transplant, and cancer. Part three is dedicated to pharmacological aspects and includes chapters on phytotherapy, and flavonoids.
Modulation of Oxidative Stress: Biochemical, Physiological and Pharmacological Aspects is a strong reference for pharma researchers in academia and industry considering leveraging modulation of oxidative stress as a strategy for the development of new drugs. Biochemists and Nutritionists may also benefit of the foundational understanding of cellular redox processes laid out.