This issue of Emergency Medicine Clinics, edited by Drs. Stephen Borron and Ziad Kazzi focuses on emergencies arising from contact with Hazardous Materials. Article topics include: Selected classes and examples of dangerous industrial chemicals, weapons of mass destruction, and their syndromic identification; Hospital preparedness for chemical and radiological disasters; Personnel protection and decontamination of adults and children; Resources for toxicological information and assistance; Asphyxiants; Corrosives and irritants; Organophosphates and carbamates; Intentional and unintentional food, drug, and water contamination, and more!.