Introductory chapters 1. Overview on chronic complications of diabetes mellitus 2. Epidemiology of chronic complications: A global perspective 3. Molecular mechanisms involved in hyperglycemia-induced cellular damage 4. Vascular calcification in diabetes mellitus: Molecular mechanisms and clinical implications Classical complications 5. Pathogenesis of diabetic atherosclerotic cardiovascular disease 6. Chronic kidney disease in diabetes: Current concepts 7. Diabetic retinopathy: New insights 8.
Macular edema: A fearful complication of diabetic eye disease 9. The eye as a mirror of neuronal impairment 10. Diabetic neuropathy: Current issues in diagnosis and prevention Non-classical complications 11. Pathophysiological and clinical aspects of non-classical targets of microangiopathy 12. Diabetic bone disease: Metabolic and microvascular damage 13. Non-alcoholic fatty liver disease: What's before and what are the consequences 14. The diabetic lung 15. Diabetic cardiomyopathy: Pathogenetic mechanisms and clinical consequences 16.
Diabetes-related cognitive impairment and dementia in diabetes 17. Cancer in diabetes: Who is who? Outlook in management issues 18. Metabolic memory: what is in it? 19. HbA1c, or glucose variability for causing diabetic complications? 20. Current perspectives on prevention of cardiovascular disease in diabetes 21. Prevention and management of chronic kidney disease in diabetes 22. Heart failure in diabetes: Current clinical management 23. Diabetic eye disease: Novel therapeutic strategies 24.
Diabetic foot disease: Recent therapeutic progress.