How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and structure? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "A growing series of excellent manuals' by Molecular Medicine Today , the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format, the FactsBooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties and biological activity. Meticulously researched and compiled by experts in the field, keeping abreast of developments has never been so easy! With The Gene Knockout FactsBook , the series brings you from the molecule in isolation to its function in the whole animal. This two volume work contains information on the phenotypes of 600 mice in which a single gene has been inactivated by targeted mutation. Mice with mutations affecting aspects of immunology, development, neurobiology, metabolism, apoptosis and cancer (amongst others) furnish valuable insights into the functions of these genes. Entries provide information on: * general description of the protein and its function * gene symbol and database accession number * knockout construct * mouse phenotype * key references.