Contributors, vii Preface, x 1 Prostate Cancer Epidemiology, 1 Annie Darves-Bornoz, Joe Park, and Aaron Katz 2 Diagnosis and Screening, 16 Yiannis Philippou, Harveer Dev, and Prasanna Sooriakumaran 3 Understanding the Histopathology, 34 Jon Oxley 4 Markers in Prostate Cancer, 49 Philippa J. Cheetham 5 Imaging, 72 Jonathan Richenberg 6 Counseling the Patient with Newly Diagnosed Prostate Cancer, Stage by Stage, 116 Nicholas James Smith and William Richard Cross 7 Active Surveillance in the Management of Low-Risk Prostate Cancer, 136 L. Boccon-Gibod 8 Radical Surgery, 145 Adnan Ali and Ashutosh Tewari 9 Radiation Therapy in the Management of Prostate Cancer, 170 J. Conibear and P.J. Hoskin 10 Novel Therapies for Localized Prostate Cancer, 191 Massimo Valerio, Mark Emberton, Manit Arya, and Hashim U. Ahmed 11 Posttherapy Follow-up and First Intervention, 211 Ernesto R. Cordeiro, Anastasios Anastasiadis, Matias Westendarp, Jean J.

M.C.H. de la Rosette, and Theo M. de Reijke 12 Managing Rising PSA in Naive and Posttherapy Patients, 230 George Thalmann and Martin Spahn 13 Diagnosis and Management of Metastatic Prostate Cancer, 245 Bertrand Tombal and Frederic Lecouvet 14 New Therapies in Hormone Relapsed Disease, 265 Carmel Pezaro, Aurelius Omlin, Diletta Bianchini, and Johann de Bono 15 End of Life Care in Prostate Cancer, 287 John D. Graham 16 The Long Perspective: Prostate Cancer as a Chronic Disease, 298 Peter Whelan 17 The Future: What's in the Toolkit for Prostate Cancer Diagnosis and Treatment?, 313 Norman J. Maitland Index, 331 Color plate section can be found facing page 148.