"Stevens and Boucher tear down barriers to programming and bioinformatics, for biologists and medics alike . this is the book that I wish I could have read years ago. Serving as both a straightforward tutorial and plain-English reference, the key programming, biology and bioinformatics concepts necessary to build programs for practical, real-world applications are explained in a logical and easy-to-follow order, helping the reader to get from zero to results faster. Unlike many programming books and resources, information is presented in the right amount of detail and jargon is demystified, giving a gentle but thorough and practical introduction to programming with Python, while providing useful tips and encouraging good practices. This introduction is built on with 'from the ground up' explanations of basic, intermediate and advanced computational biology methodologies through Python implementations, resulting in a well-rounded text for programming to solve biological challenges." Harry Jubb, University of Cambridgeniversity of Cambridgeniversity of Cambridgeniversity of Cambridge.