Uses of Dosimetry Information in Nuclear Medicine.- Diagnostic vs. Therapeutic Applications.- Model-Based vs. Patient-Based Approaches.- Practical Dosimetry: Balancing Benefits and Risks.- Clinical Utility: Interface of pPtient, Physician, and Physicist. Fundamental Concepts: Calculating Radiation Dose.

- Dosimetry Quantities and Units.- Dosimetry Systems. Models and Resources for Internal Dose Calculations.- Standardized Models for Dosimetry.- Input Data for Dose Calculations.- Standard Dose Estimates for Radiopharmaceuticals.- Modifications to the Standard Models.- The Pregnant Patient.

- The Breastfeeding Patient. Steps in Dose Calculations.- Choice and Application of Standardized Models.- Internal Dose Calculations.- Image Quantification: Human Data.- Kinetic Analysis.- Dose Calculations.- Teaching Examples.

- Image-Based, Patient-Individualized Dosimetry. Case Studies.- Development of New Diagnostic Radiopharmaceuticals.- Development of Radiopharmaceuticals for Therapy.- The Pregnant Patient. Biological Effects of Radiation.- Basic Principles.- Mechanisms of Radiation Damage to Biological Systems.

- Observed Biological Effects in Humans.- Cancer.- Cell Survival Studies.- Related Biological Effectiveness.- New Evidence: and Some Confusion!.- Use of Radiation Dosimetry in Patient Therapy Treatment Planning. Regulatory Aspects of Dose Calculations.- The Philosophy of Radiation Protection.

- Scientific Advisory Bodies.- Regulatory Bodies.