Part I. History and Growth of Genetic Medicine 1. Documentation of units of inheritance and their contribution to phenotype 2. Early documentation of inherited disorders through family studies 3. Discoveries in physiology, biochemistry, protein and enzyme studies between 1920-1970 4. Early translation of biochemical, metabolic and genetic discoveries into clinical medicine 5. Advances in methods of genome analyses, nucleotide analyses and implications of variants Part II. Clinical Applications of Genomic Medicine 6.

Expansion of use of genome analyses and sequencing to diagnosis of genetic diseases 7. Improved analyses of regulatory genome, transcriptome and gene function, mutation penetrance and clinical applications 8. Standardized phenotype documentation, documentation of genotype phenotype correlations 9. Expansion of methods of gene editing therapy and analysis of safety and efficacy 10. Public health applications of genetics including newborn screening and documentation of gene environment interactions 11. Analysis of variants associated with abnormal drug responses, genetics and genomics in drug design 12. Genetic and genomic medicine relevance to cancer prevention, diagnosis, and treatment 13. Benefits of the incorporation of genomic medicine in clinical practice 14.

Using insights from genomics to increase possibilities for treatment of genetic diseases.