Foreword: Yehuda Shoenfeld and M. Eric Gershwin. Part I: Organ-Specific Autoimmune Diseases:. 1. Activation, Apoptosis, and Clearance of Neutrophils in Wegener''s Granulomatosis: André P. van Rossum, Pieter C. Limburg, and Cees G. M.
Kallenberg. 2. Is PR3-ANCA Formation Initiated in Wegener''s Granulomatosis Lesions? Granulomas as Potential Lymphoid Tissue Maintaining Autoantibody Production: J Voswinkel, A Müller, and P Lamprecht. 3. Clinical Relevance of Antiphospholipid Antibodies in Primary Biliary Cirrhosis: Philipp von Landenberg, Michael Baumgartner, Juergen Schoelmerich, Karl J. Lackner, and Reinhild Klein. 4. IL-10 and the Cytokine Network in the Pathogenesis of Human Autoimmune Hemolytic Anemia: Caterina Toriani-Terenzi and Enzo Fagiolo.
5. Crohn''s Disease Is Associated with Polymorphism of CARD15/NOD2 Gene in a Hungarian Population: Zsuzsanna Nagy, Oszkár Karádi, György Rumi, György Rumi, Jr., Alajos Pár, Gyula Mózsik, László Czirják, and Gábor Süto. 6. Apoptosis in Human Skin: Role in Pathogenesis of Various Diseases and Relevance for Therapy: Esther Reefman, Pieter C. Limburg, Cees G. M. Kallenberg, and Marc Bijl.
7. Cancer-Associated Myositis: Clinical Features and Prognostic Signs: Andrea Ponyi, Tamás Constantin, Miklós Garami, Csilla andrás, Béla Tállai, Andrea Váncsa, Lajos Gergely, and Katalin Dankó. 8. Control of Type 1 Autoimmune Diabetes by Naturally Occurring CD4+CD25+ Regulatory T Lymphocytes in Neonatal NOD Mice: C A Piccirillo, M Tritt, E Sgouroudis, A Albanese, M Pyzik, and V Hay. 9. The Role of Methallothioneins in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis: Carmen Espejo and Eva M. Martínez-Cáceres. 10.
Oxidized Low-Density Lipoprotein/ß2-Glycoprotein I Complexes and Autoantibodies in Patients with Type 2 Diabetes Mellitus: Luis R. Lopez, Beth L. Hurley, Daniel F. Simpson, and Eiji Matsuura. 11. Autoantibodies to Human 6 Integrin in Patients with Bullous Pemphigoid: Mária Kiss, Ádám Perényi, Ilona Marczinovits, János Molnár, Attila Dobozy, Lajos Kemény, and Sándor Husz. 12. Soluble HLA Class I and Class II Molecules in Relapsing-Remitting Multiple Sclerosis: Acute Response to Interferon-ß1a Treatment and Their Use as Markers of Disease Activity: Alireza Minagar, Irena Adamashvilli, Stephen L.
Jaffe, Michael F. Glabus, Eduardo Gonzalez-Toledo, and Roger E. Kelley. 13. Proinflammatory Cytokines and Autoimmunity in Churg-Strauss Syndrome: B Hellmich, E Csernok, and W L Gross. 14. Rheumatic Fever: How S. pyogenes-Primed Peripheral T Cells Trigger Heart Valve Lesions: L Guilherme, K C Faé, S E Oshiro, A C Tanaka, P M A Pomerantzeff, and J Kalil.
15. Avidity of Anti-ß2-Glycoprotein I and Thrombosis or Pregnancy Loss in Patients with Antiphospholipid Syndrome: S Cucnik, B Bozic, T Kveder, M Tomsic, and B Rozman. 16. Neurological Complications of Celiac Disease and Autoimmune Mechanisms: Preliminary Data of a Prospective Study in Adult Patients: C Briani, G Zara, E Toffanin, S Ruggero, A Ferrarini, F De Lazzari, M Luca, D Faggian, F Grassivaro, M Ermani, R Pezzani, B Giometto, and A D''odorico. 17. E2F1-/- C57BL/6 Mice Overexpressing a Human Bcl-2 Transgene in B Cells Develop a Mild Autoimmune Syndrome: María J. Marín, Itxaso García, Marta Peña, Ainhoa Bolívar, Ana Zubiaga, and Marcos Lóez-Hoyos. 18.
Systemic Thromboembolism in Inflammatory Bowel Disease: Mechanisms and Clinical Applications: Gilad Twig, Gisele Zandman-Goddard, Martine Szyper-Kravitz, and Yehuda Shoenfeld. 19. Pregnancy Loss and Endometriosis: Pathogenic Role of Anti-Laminin-1 Autoantibodies: Junko Inagaki, Akane Kondo, Luis R. Lopez, Yehuda Shoenfeld, and Eiji Matsuura. 20. Primary Biliary Cirrhosis: Solving the Enigma: Alessia Giorgini, Carlo Selmi, Pietro Invernizzi, Mauro Podda, Massimo Zuin, and M Eric Gershwin. 21. The Stages of Type 1A Diabetes: Naru Babaya, Maki Nakayama, and George S.
Eisenbarth. 22. Soluble CD40L in Plasma of Patients with Primary Biliary Cirrhosis: Sabine Oertelt, Pietro Invernizzi, Carlo Selmi, Mauro Podda, and M Eric Gershwin. 23. Decreased Serum Leptin Levels in Primary Biliary Cirrhosis: A Link between Metabolism and Autoimmunity?: Roman Rieger, Sabine Oertelt, Carlo Selmi, Pietro Invernizzi, Mauro Podda, and M Eric Gershwin. 24. Analysis of the Foxp3/Scurfin Gene in Crohn''s Disease: Ogyi Park, Irina Grishina, Patrick S. Leung, M Eric Gershwin, and T Prindiville.
Part II: Systematic Autoimmune Diseases:. 25. Juvenile Systemic Sclerosis: A Follow-up Study of Eight Patients: Szilvia Szamosi, László Maródi, László Czirják, Zoltán Ellenes, and Gabriella Szücs. 26. Antifodrin Antibodies in Sjögren''s Syndrome: A Review: Torsten Witte. 27. Generation and Characterization of Three Monoclonal IgM Antiphospholipid Antibodies Recognizing Different Phospholipid Antigens: Catharina Buschmann, Christian Fischer, Viola Ochsenhirt, Carolin Neukirch, Karl J. Lackner, and Philipp von Landenberg.
28. Premature Immunosenescence in Rheumatoid Arthritis and Multiple Sclerosis Patients: Marielle Thewissen, Loes Linsen, Veerle Somers, Piet Geusens, Jef Raus, and Piet Stinissen. 29. Association of Rheumatoid Arthritis with HLA-DR1 and HLA-DR4 in Hungary: Anikó Kapitány, Erika Zilahi, Sándor Szántó, Gabriella Szücs, Zoltán Szabó, Anikó Végvári, Péter Rass, Sándor Sipka, Gyula Szegedi, and Zoltán Szekanecz. 30. Plasminogen Activator Inhibitor-1 Is Associated with Impaired Endothelial Function in Women with Systemic Lupus Erythematosus: Emily C. Somers, Wendy Marder, Mariana J. Kaplan, Robert D.
Brook, and W Joseph McCune. 31. Early Atherosclerosis in Rheumatoid Arthritis: Effects of Smoking on Thickness of the Carotid Artery Intima Media: Roberto Gerli, Yaniv Sherer, Gaetano Vaudo, Giuseppe Schillaci, Boris Gilburd, andrea Giordano, Elena Bartoloni Bocci, Rosita Allegrucci, Simona Marchesi, Elmo Mannarino, and Yehuda Shoenfeld. 32. Investigation of Arthritic Joint Destruction by a Novel Fibroblast-Based Model: U Sack, B Sehm, F Kahlenberg, A Murr, J Lehmann, A Tannapfel, K Uberla, A Moessner, A Dietrich, F Emmrich, F Lange, A Jungel, J-M Braun, and U Anderegg. 33. Prevalence of Antiphospholipid and Antioxidized Low-Density Lipoprotein Antibodies in Rheumatoid Arthritis: Yaniv Sherer, Roberto Gerli, Gaetano Vaudo, Giuseppe Schillaci, Boris Gilburd, andrea Giordano, Elena Bartoloni Bocci, Rosita Allegrucci, Simona Marchesi, Elmo Mannarino, and Yehuda Shoenfeld. 34.
Mono-organic versus Multi-organic Involvement in Primary Antiphospholipid Syndrome: Gabriela Medina, Olga Vera-Lastra, Ulises Angeles, and Luis J. Jara. 35. OxLDL/ß2GPI Complexes and Autoantibodies in Patients with Systemic Lupus Erythematosus, Systemic Sclerosis, and Antiphospholipid Syndrome: Pathogenic Implications for Vascular Involvement: Luis R. Lopez, Daniel F. Simpson, Beth L. Hurley, and Eiji Matsuura. 36.
Anti-HSP60 Immunity Is Already Associated with Atherosclerosis Early in Life: M Knoflach, D Bernhard, and G Wick. 37. Determinants of Vessel Targeting in Vasculitis: Gary S. Hoffman. 38. Lymphocyte Activation as a Possible Measure of Atherosclerotic Risk in Patients with Sleep Apnea: Larissa Dyugovskaya, Peretz Lavie, and Lena Lavie. 39. Systemic Lupus Erythematosus, Atherosclerosis, and Autoantibodies: Sandra Zampieri, Luca Iaccarino, Anna Ghirardello, Elena Tarricone, Silvia Arienti, Piercarlo Sarzi-Puttini, Pierfranca Gambari, and andrea Doria.
40. Accelerated Atherosclerosis in Patients with Systemic Autoimmune Diseases: Karina de Leeuw, Cees Kallenberg, and Marc Bijl. 41. Nocturnal Hormones and Clinical Rhythms in Rheumatoid Arthritis: Maurizio Cutolo, Kati Otsa, Oivi Aakre, and Alberto Sulli. 42. Xenobiotic-Induced Recruitment of Autoantigens to Nuclear Proteasomes Suggests a Role for Altered Antigen Processing in Scleroderma: Min Chen and Anna von Mikecz. 43. Humoral Antigenic Targets of the Ribosomal P0 Lupus Autoantigen Are Not Limited to the Carboxyl Region: Benjamin F.
Bruner, Donny M. Wynn, Morris Reichlin, John B. Harley, and Judith A. James. 44. Clinical Correlations of Potential Activity Markers in Systemic Sclerosis: R Becvár, J Stork, V Pesáková, A Stánová, H Hulejová, L Rysová, A Zatloukalová, P Zatloukal, M Jáchymová, and L Pourová. 45. Complement Activation: A Novel Pathogenic Mechanism in the Antiphospholipid Syndrome: Silvia S.
Pierangeli, Mariano Vega-Ostertag, Xiaowei Liu, and Guillermina Girardi. 46. The Interplay of Chemokines and Dendritic Cells in the Pathogenesis of Lupus Nephritis: Marco Tucci, Nicola Calvani, Hanno B. Richards, Cosima Quatraro, and Franco Silvestris. 47. Cellular and Molecular Mechanisms of Regulation of Autoantibody Production in Lupus: Bevra H. Hahn, Fanny Ebling, Ram R. Singh, Ram P.
Singh, George Karpouzas, and Antonio La Cava. 48. The Role of Innate and Adaptive Immunity to Oxidized Low-Density Lipoprotein in the Development of Atherosclerosis: Kazuko Kobayashi, Luis R. Lopez, Yehuda Shoenfeld, and Eiji Matsuura. 49. Predictive Markers for Development of Severe Organ Involvement in Patients with Systemic Sclerosis: Laure Ysebrant De Lendonck, Annick Ocmant, Florence Roufosse, and Elie Cogan. 50. Hughes Syndrome, the Antiphospholipid Syndrome: A New Chapter in Neurology: Giovanni Sanna, Maria Laura Bertolaccini, and Graham R.
V. Hughes. 51. New Facet of Antiphospholipid Antibodies: Guido Valesini and Cristiano Alessandri. Part III: Treatment:. 52. Inhibitor Development in Patients with Hemophilia A after Continuous Infusion of FVIII Concentrates: CH von Auer, J Oldenburg, M von Depka, C Escuriola-Ettinghausen, K Kurnik, H Lenk, and I Scharrer.<.