Mary Jane Seacole (23 November 1805 - 14 May 1881), nee Grant, was a Jamaican-born woman of Scottish and Creole descent who set up a "British Hotel" behind the lines during the Crimean War, which she described as "a mess-table and comfortable quarters for sick and convalescent officers," and provided succor for wounded servicemen on the battlefield. She was posthumously awarded the Jamaican Order of Merit in 1991. In 2004 she was voted the greatest black Briton. She acquired knowledge of herbal medicine in the Caribbean. When the Crimean War broke out, she applied to the War Office to assist but was refused. She traveled independently and set up her hotel and assisted battlefield wounded. She became extremely popular among service personnel who raised money for her when she faced destitution after the war. After her death, she was forgotten for almost a century, but today is celebrated as a woman who successfully combated racial prejudice.

Her biography, Wonderful Adventures of Mrs. Seacole in Many Lands (1857), is one of the earliest autobiographies of a mixed-race woman, although some aspects of its accuracy have been questioned. It has been claimed that Seacole's achievements have been exaggerated for political reasons and a plan to erect a statue of her at St Thomas' Hospital, London, describing her as a "pioneer nurse," has generated controversy. Further controversy broke out in the United Kingdom late in 2012 over reports of a proposal to remove her from the country's National Curriculum".