This book presents a series of coordinated studies that explain and illustrate how philosophy must be developed systematically with its problems and topics bound together by links of reciprocal interconnection. The book consists of two parts: The first part consists of a series of case studies which illustrate how philosophical issues do not remain in neatly separated compartments but reach out in interrelationship with one another. The second part analyzes the principle resources of philosophical methodology and shows in detail how and why they can only be implemented in a systemically interrelated manner. Overall, the book demonstrates and illustrates the systemic and holistic nature of philosophical inquiry. Nicholas Rescher is Distinguished University Professor of Philosophy at the University of Pittsburgh, USA. In a productive research career extending over six decades, he has well over one hundred books to his credit, including Philsophical Fallacies (Palgrave, 2022), Ethics Matters (Palgrave 2021), Philosophical Clarifications (Palgrave 2019), and Value Reasoning (Palgrave 2017).