INTEGRATION OF THE MUSCULOSKELETAL AND NEUROLOGICAL SYSTEMS Introduction Entry of Environmental Pollutants: External and Internal Mechanisms of the Total Body Pollutant Load External Pollutants Internal Excitotoxins Environmental Control for Reducing Total Body Load ECU Construction and Maintenance Use of the ECU Summary VASCULAR FUNCTION AND DYSFUNCTION Introduction to the Cardiovascular System in Chemical Sensitivity Physiology and Pollutant Damage to Vascular Perfusion: Changes in the Sympathetic Nervous System Function Physiology of Vascular Perfusion Autonomic Nervous System Connective Tissue Endothelins Vascular Injury due to Pollutants Neovascularization Regional Perfusion Injury Blood Volume Effects of Pollutants on the Clotting System Oxygen Extraction Effects of Pollutants on Myocardial Cells Types of Mechanisms in Vascular Damage Nonimmune Mechanisms Immune Mechanisms Effects of Endocrine on the Vascular System Pollutant Entry in Dyshomeostasis: Clinical Syndromes Vasculitis Small Vessel Vasculitis Large Vessel Vasculitis Hypersensitive Vasculitis Eosinophilic Vasculitis Recurrent Phlebitis Cardiac Arrhythmias and Dysfunction Sudden Cardiac Death Hereditary Angioedema Urticaria Anaphylaxis Cardiac Metabolic Syndrome Cardiomyopathy Myocarditis Atherosclerosis Environmental Aspects of Atherosclerosis Cardiac Events and Hospital Admission Changes in Heart Rate and Cardiac Function Influence of Particulates Pathophysiology Leading to Inflammation Inflammation Mechanism Myocardial Necrosis and Toxic Infarction Cardioprotection Apoptosis Toxic Infarction Triggering Agents of CAD Heart Failure Introduction Heart Failure Pathology and Cell Communication Heart Failure Pathophysiology Energy-Starvation Hypothesis Heart Failure Treatment Classic Medical Treatment Neural Humeral Activation Emerging Therapeutic Options: Nutrients Summary Index ular Injury due to Pollutants Neovascularization Regional Perfusion Injury Blood Volume Effects of Pollutants on the Clotting System Oxygen Extraction Effects of Pollutants on Myocardial Cells Types of Mechanisms in Vascular Damage Nonimmune Mechanisms Immune Mechanisms Effects of Endocrine on the Vascular System Pollutant Entry in Dyshomeostasis: Clinical Syndromes Vasculitis Small Vessel Vasculitis Large Vessel Vasculitis Hypersensitive Vasculitis Eosinophilic Vasculitis Recurrent Phlebitis Cardiac Arrhythmias and Dysfunction Sudden Cardiac Death Hereditary Angioedema Urticaria Anaphylaxis Cardiac Metabolic Syndrome Cardiomyopathy Myocarditis Atherosclerosis Environmental Aspects of Atherosclerosis Cardiac Events and Hospital Admission Changes in Heart Rate and Cardiac Function Influence of Particulates Pathophysiology Leading to Inflammation Inflammation Mechanism Myocardial Necrosis and Toxic Infarction Cardioprotection Apoptosis Toxic Infarction Triggering Agents of CAD Heart Failure Introduction Heart Failure Pathology and Cell Communication Heart Failure Pathophysiology Energy-Starvation Hypothesis Heart Failure Treatment Classic Medical Treatment Neural Humeral Activation Emerging Therapeutic Options: Nutrients Summary Index ;lt;BR>Anaphylaxis Cardiac Metabolic Syndrome Cardiomyopathy Myocarditis Atherosclerosis Environmental Aspects of Atherosclerosis Cardiac Events and Hospital Admission Changes in Heart Rate and Cardiac Function Influence of Particulates Pathophysiology Leading to Inflammation Inflammation Mechanism Myocardial Necrosis and Toxic Infarction Cardioprotection Apoptosis Toxic Infarction Triggering Agents of CAD Heart Failure Introduction Heart Failure Pathology and Cell Communication Heart Failure Pathophysiology Energy-Starvation Hypothesis Heart Failure Treatment Classic Medical Treatment Neural Humeral Activation Emerging Therapeutic Options: Nutrients Summary Index amp;lt;BR> Index.