The scope of neuropathology continues to expand, as The text is divided into three main sections. The first evidenced by increasing numbers of multivolume and part(chapters1-11)presents,inoutlineform,basicupdated specialtytexts,whichhavebeenpublishedinrecentyears. informationonthespectrumofneurologic-relateddisease. Forthoseintheneurosciencedisciplines,theeverincreasing The second part (chapters 12 and 13) presents pertinent amountofinformationoneneedstoassimilateandmaster pictoralexamplesofaspectrumofneuropathologiccon- canbechallengingandevenattimesdaunting. tionsinaquestionformatwithanswersandbriefexplanation As with the first edition, the second edition of provided. A CD is included that contains two interactive Neuropathology Review attempts to summarize, in outline tests composed of questions and answers given in several form, the essentials of neuropathology. The objective is chaptersfromthisbook,aswellascolorversionsofimages twofold: 1) to provide an overview of neuropathology for foundinthevolume. Thefinalsection(chapters14and15) thoseinitiallyencounteringthedisciplineand,2)toprovidea includesaseriesofwrittenquestionswithprovidedanswers frameworkforreviewforthosepreparingforin-serviceand andexplanationsinordertoreviewthematerialpresentedin boardexaminationsinthedisciplinesofneurology,neuro- thefirstsectionofthetext.
Newquestionshavebeenadded surgery,andpathology,whichrequiresomeknowledgeof to the bank of questions previously published in the first neuropathology. Neuropathologyisadynamicfield. There addition. isaconstantemergenceofnewinformationandideasthat TheauthorwouldliketothankMs. DeniseEgletonfor continuetoshapeourunderstanding. Thisnecessitatesthe herhelpinpreparingthismanuscript. ThanksalsotoLaureen periodicupdatingofatextsuchasthistokeepabreastof Nemethforherexpertassistancewiththeillustrations. thechanges.
RichardPrayson vii Contents Preface. vii CompanionCD. xi 1 NormalHistology. 1 2 VascularLesions. 7 3 Tumors. 13 4 Trauma. 31 5 CongenitalMalformations,PerinatalDisease, andPhakomatoses. 35 6 DemyelinatingandDysmyelinatingDiseases.
45 7 MetabolicandToxicDiseases. 51 8 DegenerativeDisease. 57 9 Infection. 63 10 SkeletalMuscle. 71 11 PeripheralNerve. 81 12 FiguresWithQuestions. 87 13 AnswerstoFiguresWithQuestions. 203 14 WrittenSelf-AssessmentQuestions.
213 15 AnswerstoWrittenSelf-AssessmentQuestions. 233 SelectedReferences. 241 Index. 243 ix CompanionCD This CD-ROM contains an interactive study guide. The does not support an auto-start feature. The following ha- applicationiscompatiblewithmostMacandPCcomputers. ware and software are the minimum required to use this CD-ROM: PCUsers:Theapplication"HP_Prayson. exe"shouldlaunch * For Microsoft Windows: An Intel Pentium II with 64 automatically on most Windows computers when the disc MBofavailableRAMrunningWindows98,oranIntel is inserted into your computer.