Recent advances in molecular pharmacology and brain imaging have revolutionized our understanding of how psychoactive drugs work. These developments have been integrated into a new undergraduate text from the authors of the widely acclaimed Principles of Neuropsychopharmacology. Psychopharmacology: Drugs, the Brain, and Behavior is unique in its breadth of coverage, ranging from historical accounts of drug use to clinical and pre-clinical behavioral studies to the latest research on drug effects in transgenic mouse models. Student engagement with the material is fostered by opening each chapter with a relevant vignette and by providing breakout boxes presenting novel or cutting-edge topics for special discussion. The book is richly illustrated with numerous full-colour photographs and line art depicting important concepts and experimental data.