There is a problem in Egypt. Cat burglars have stolen all the cats. The police can't find them, and Frisky and Holly are called into action. They start at the great Pyramid where the cat burglars were last seen. The clues take them through the pyramid, where they find a lost kitten who had fallen out of one of the bags. The kitten wants to find its family, so the heroes bring it along. They go to the Sphinx, and up the Nile River to the Valley of the Kings. Here they find the final clue which is hidden in King Tut's tomb.

It sends them to the baggage area of the airport where the cats are being taken out of the country in suitcases. But there are hundreds of bags waiting for flights and the dogs figure out which bags contain the cats. The cats are found and released, and the little kitten is reunited with its family. The cat burglars see the cats are escaping and a chase begins. Frisky and Holly stop them, and the cats are returned home. Both dogs are a little wiser, having learned the value of doing the right thing and the power of teamwork.