Careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. Nanoparticle-Based Drug Delivery in Cancer Treatment discusses nanotechnological developments of interfering RNA-based nanoparticles and delivery vehicles, validated therapeutic RNAi-molecular target interactions, and explains the results of clinical and preclinical trials. The book also gives strategies which might be universal methods for constructing hybrid organic-inorganic nanomaterials and can be widely applied in biomedical field. Key Features: Reviews recent advances of nanoparticle-mediated siRNA delivery systems and their application in clinical trials for cancer therapy. Focuses on material platforms that establish NPs and both localized and controlled gene silencing. Emphasizes the most promising systems for clinical translation. Surveys progress in nanoparticle-based nanomedicine in cancer treatment. Describes the most advanced of the non-viral nanocarriers for delivery of oligonucleotides to malignant blood cancer cells.

This book is a valuable resource for researchers, professors, and students researching drug delivery, gene carriers, cancer therapy, nanotechnology, and nanomaterials.