This issue of Archai is concerned with the rise of the disenchanted world view in the modern era, and the possible significance of archetypal cosmology for moving beyond it. The articles featured here approach the topic of disenchantment and its transcendence from two overlapping perspectives: conceptual, exploring archetypal astrology's relationship to modern philosophical and scientific thought; and as historical narrative, focusing on the psychospiritual, existential, cultural, and cosmological dimensions of Western civilization's journey from the Christian world view through nihilism and disenchantment to the unfolding spiritual transformation at the turn of the twentieth century and on, finally, to consider the life experience of a prominent modern physicist.