From the New York Times bestselling author of Still Alice Lisa Genova comes a powerful and transcendent new novel about a family struggling with the impact of Huntingtons disease.Joe OBrien is a forty-four-year-old police officer from the Irish Catholic neighborhood of Charlestown, Massachusetts. A devoted husband, proud father of four children in their twenties, and respected officer, Joe begins experiencing bouts of disorganized thinking, uncharacteristic temper outbursts, and strange, involuntary movements. He initially attributes these episodes to the stress of his job, but as these symptoms worsen, he agrees to see a neurologist and is handed a diagnosis that will change his and his familys lives forever: Huntingtons disease. Huntingtons is a lethal neurodegenerative disease with no treatment and no cure. Each of Joes four children has a 50 percent chance of inheriting their fathers disease, and a simple blood test can reveal their genetic fate. While watching her potential future in her fathers escalating symptoms, twenty-one-year-old daughter Katie struggles with the questions this test imposes on her young adult life. Does she want to know? What if shes gene positive? Can she live with the constant anxiety of not knowing? As Joes symptoms worsen and hes eventually stripped of his badge and more, Joe struggles to maintain hope and a sense of purpose, while Katie and her siblings must find the courage to either live a life at risk or learn their fate.

Praised for writing that explores the resilience of the human spirit (The San Francisco Chronicle), Lisa Genova has once again delivered a novel as powerful and unforgettable as the human insights at its core.