Mechanisms of Lymphocyte Activation and Immune Regulation
Mechanisms of Lymphocyte Activation and Immune Regulation
Click to enlarge
Author(s): Fauci, Anthony
Gupta, Sudhir
ISBN No.: 9781468453256
Pages: ix, 337
Year: 201212
Format: Trade Paper
Price: $ 158.12
Dispatch delay: Dispatched between 7 to 15 days
Status: Available

T Cell Receptor.- The T cell receptor: Its repertoire and role in thymocyte development.- Murine T-cell receptor genes.- Correspondence between functionally significant sequences in immunoglobulin and the T cell receptor for antigen.- T Cell Activation.- The early mitogenic pathway in mouse thymocytes: An analysis of the dual signal hypothesis.- The role of the antigen receptor/T3 complex in T-cell activation.- Early events in lymphocyte activation triggered via CD3/Ti or CD2.


- Human T lymphocyte activation.- Transmembrane signals in the activation of T lymphocytes.- Ion channels in T lymphocytes.- Interleukins and their Receptors.- The multiple biological properties of interleukin-1 influencing immunocompetent cells.- Autocrine growth function of interleukin-1-like molecules secreted by neoplastic human B cells.- Dissection of the molecular events occuring during T cell cycle progression.- The Interleukin-2 receptor on normal and malignant lymphocytes.


- IL-2 receptor gene activation by ATL-derived factor (ADF).- Mechanisms in interleukin 3 regulated growth and differentiation.- B Lymphocyte Activation, Proliferation and Differentiation.- The activation, proliferation, and differentiation of human B lymphocytes.- Delineation of human B cell differentiation: Immunological and molecular characterization of human B cell differentiation factor (BSF-2).- Transmembrane signaling reactions generated in B cells in response to anti-IgM or lipopolysaccharide.- Coupling of B cell surface Ig, Ia and BSF1 receptors to intracellular "second messengers".- B lymphocyte activation -- The roles of receptor cross-linkage and BSF-1.


- B cell growth factor interactions.- IgGl induction factor: A single molecular entity with multiple biological functions.- Inhibition of human B cell proliferation by ion channel blockers.- Proto-Oncogenes and Cellular Activation and Differentiation.- Cell growth associated regulation of c-myc and c-fos in normal human T cells.- Regulation of proto-oncogene expression during T lymphocyte activation and proliferation.- Expression of the c-fos gene during differentiation.- Natural Killing and Cyclosporin A.


- Activation of natural killer (NK) cells and mechanism of their cytotoxic effects.- Regulation of activation and proliferation of human natural killer cells.- Molecular mechanism of natural killer cell-mediated cytotoxicity.- Mechanism of action of cyclosporine.- Contributors.


To be able to view the table of contents for this publication then please subscribe by clicking the button below...
To be able to view the full description for this publication then please subscribe by clicking the button below...