Based on the author's study of some 200 patients, and on a detailed review of the literature, this volume examines all aspects of Duchenne muscular dystrophy--the second most common genetic disorder affecting humans. Topics include the history of the disease, clinical features, involvement of tissues other than muscle, laboratory investigations, differential diagnosis, biochemistry, pathogenesis, genetics, molecular pathology, prevention, genetic counselling, and surgical and medical management. The book is illustrated with numerous photographs and line drawings, and includes an extensive bibliography.