The sensitive perception of a society's artistic expressions facilitates our comprehension of its ethos, enabling the meaningful communication between individuals and communities, which is the fundamental link that connects human beings.This book investigates the spirit of Mesoamerican civilization from pre-history until the 20th century, interpreting its architectural legacy, both in the planned environments of the public plazas, and in the art that is integrated into structural designs, exemplified by the Mexican mural paintings. The first part studies the open areas defined by substantially symbolic architecture, providing the spatial forum for the spiritual and consequential collective manifestations of the native population throughout the history of Mesoamerica, linking past, present, and future generations. The second part focuses on mural painting, which has been a consistent universal medium for eloquent cultural interaction among Mesoamericans.