This fascinating book examines 'cabin fever' in the wake of the coronavirus pandemic and the greatest confinement of people to their homes in history. Exploring the definitions and social and cultural history of cabin fever, the book discusses its origins emerging from physical afflictions like typhus through to the use of the term to refer to psychological responses to prolonged isolation or confinement. Offering insights on cabin fever in different contexts (at sea, on land, in the air and in space) the book draws on an array of evidence of the impact of this folk syndrome. In the brunt of the pandemic, it has become increasingly clear that adapting to lockdown has become a matter of personal and public endurance and creativity. This book provides an important account of the threat of cabin fever in the pandemic and provides the best-known antidotes for it.