In May 1973, Assata Olugbala Shakur was involved in a shootout on the New Jersey Turnpike in which she was accused of killing New Jersey State Trooper Werner Foerster and assaulting Trooper James Harper. This resulted in her indictment of first-degree murder of Foerster and seven other felonies related to the shootout. A member of the Black Panther Party, she became a prime target of the Federal Bureau of Investigations Counterintelligence Program. When she joined the Black Liberation Army and went into hiding, between 1973 and 1977, she was placed on the FBIs Most Wanted List for three bank robberies, the kidnapping and murder of two drug dealers, and the attempted murder of two New Jersey police officers. In March 1977 Assata Shakur was convicted of murdering state trooper Werner Forrester and was imprisoned. Two years later she broke out of the maximum-security wing of Clinton Correctional Facility in New Jersey, pistol in hand, as she and three cohorts sped out of the prison grounds. In 1984 she was granted political asylum in Cuba where she has lived ever since. On May 2, 2013, the FBI added her to the Most Wanted Terrorist List, the first woman to be listed.

"Assata Shakur: A 20th Century Escaped Slave" is the story of Assata Shakur, before she became a fugitive and since.