Contributors Acknowledgments Preface PART 1: CARDIOVASCULAR DISEASE: PAST, PRESENT, AND FUTURE 1. A History of the Heart, Cardiac Diseases, and the Development of Cardiovascular Medicine as a Specialty, Robert A. Harrington, Mark E. Silverman, and Charles F. Wooley 2. The Burden of Increasing Worldwide Cardiovascular Disease, Justin P. Zachariah, Ramachandran S. Vasan, and Ralph B.
D''Agostino 3. Assessing and Improving the Quality of Care in Cardiovascular Medicine, Lakshmi Venkitachalam, Amit P. Amin, and John A. Spertus Part 2: FOUNDATIONS OF CARDIOVASCULAR MEDICINE 4. Functional Anatomy of the Heart, Joseph F. Malouf, William D. Edwards, A. Jamil Tajik, and James B.
Seward 5. Normal Physiology of the Cardiovascular System, Brian D. Holt and Richard A. Walsh 6. Principles of Molecular Cardiology, Mukesh K. Jain, Aaron Proweller, and Richard A. Walsh 7. Molecular and Cellular Biology of the Normal, Hypertrophied, and Failing Heart, Saptarsi M.
Haldar and Richard A. Walsh 8. Biology of the Vessel Wall, Kathy K. Griendling, David G. Harrison, and R. Wayne Alexander 9. Molecular Development of the Heart, Bradley B. Keller, James B.
Hoyling, and Roger K. Markwald 10. Genetic Basis for Cardiovascular Disease, Robert Roberts and Elizabeth McNally 11. Tissue Regeneration of the Cardiovascular System and Stem Cells, Arjun Deb, Helmut Drexler, Mirotsou Maria, and Victor Dzau PART 3: EVALUATION OF THE PATIENT 12. Diagnostic Decision Making Using Modern Technology, Steve L. Liao and Mario J. Garcia 13. Therapeutic Decision Making Based Upon Clinical Trials and Clinical Practice Guidelines, Ira S.
Nash, Michael E. Farkouh, and Valentin Fuster 14. The History, Physical Examination, and Cardiac Auscultation, Richard A. Walsh, Robert A. O''Rourke, and James A. Shaver 15. Surface Electrocardiography, Antoni Bayés-de-Luna, Diego Goldwasser, Miquel Fiol, and Antoni Bayés-Genis 16. ECG Exercise Testing, Michael J.
Lipinski and Victor F. Froelicher 17. Cardiac Radiography, Robert A. O''Rourke 18. Echocardiography, Anthony N. DeMaria and Daniel G. Blanchard 19. Cardiac Catherization, Cardiac Angiography, and Coronary Blood Flow and Pressure Measurements, Morton J.
Kern and Spencer B. King III 20. Coronary Intravascular Imaging, Marco A. Costa, Hector M. Garcia-Garcia, and Patrick W. Serruys 21. Nuclear Cardiology, Daniel S. Berman, Sean W.
Hayes, Rory Hachamovitch, Leslee J. Shaw, and Guido Germano 22. Computed Tomography of the Heart, Melissa A. Daubert, Michael Poon, and Matthew J. Budoff 23. Magnetic Resonance Imaging of the Heart, Han W. Kim, Afshin Farzaneh-Far, Igor Klem, Wolfgang Rehwald, and Raymond J. Kim 24.
Magnetic Resonance Imaging and Computed Tomography of the Vascular System, Fabien Hyafil, Jean-Christophe Cornily, James H.F. Rudd, Valentin Fuster, and Zahi A. Fayad 25. Positron Emission Tomography for the Noninvasive Study and Quantitation of Myocardial Blood Flow and Metabolism in Cardiovascular Disease, Heinrich R. Schelbert PART 4: HEART FAILURE 26. Pathophysiology of Heart Failure, Gary S. Francis, W.
H. Wilson Tang, and Richard A. Walsh 27. The Epidemiology and Diagnosis of Heart Failure, Owais Dar and Martin R. Cowie 28. Diagnosis and Management of Heart Failure, William T. Abraham and Ayesha Hasan 29. Cardiac Transplantation, Michael X.
Pham, Gerald J. Berry, and Sharon A. Hunt 30. Surgical Treatment of Heart Failure and Mechanical Ventricular Support, David Joyce, Hari R. Mallidi, and Sharon A. Hunt PART 5: CARDIOMYOPATHY AND SPECIFIC HEART MUSCLE DISEASES 31. Classification of Cardiomyopathies, Barry J. Maron and Gaetano Thiene 32.
Dilated Cardiomyopathies, Luisa Mestroni, Edward M. Gilbert, Brian D. Lowes, and Michael R. Bristow 33. Hypertrophic Cardiomyopathy, Steve R. Ommen, Rick A. Nishimura, and A. Jamil Tajik 34.
Restrictive, Obliterative, and Infiltrative Cardiomyopathies, Brian D. Hoit 35. Myocarditis and Specific Cardiomyopathies, Sean P. Pinney and Donna M. Mancini PART 6: RHYTHM AND CONDUCTION DISORDERS 36. Genetics of Channelopathies and Clinical Implications, Silva G. Priori and Carlo Napolitano 37. Anatomy of Electrophysiology, Siew Yen Ho nad Anton E.
Becker 38. Mechanisms of Cardiac Arrhythmias and Conduction Disturbances, Peng-Sheng Chen and Charles Antzelevitch 39. Approach to the Patient With Cardiac Arrhythmias, Eric N. Prystowsky and Richard I. Fogel 40. Atrial Fibrillation, Atrial Flutter, and Atrial Tachycardia, Eric N. Prystowsky, Benzy J. Padanilam, and Albert L.
Waldo 41. Supraventricular Tachycardia: Atrioventricular Nodal Reentry and Wolff-Parkinson-White Syndrome, Hugh Calkins 42. Ventricular Arrhythmias, Robert W. Rho and Richard L. Page 43. Bradyarrhythmias and Pacemakers, Pugazhendhi Vijayaraman and Kenneth A. Ellenbogen 44. Electrophysiology and Cather-Ablative Techniques, Usha B.
Tedrow, Samuel J. Asirvatham, and William G. Stevenson 45. Antiarrhythmic Drugs, Peter R. Kowey and Gan-Xin Yan 46. Indications and Techniques of Electrical Defibrillation and Cardioversion, Richard E. Kerber 47. Arrhythmias in Children and in Patients With Congenital Heart Disease, Timothy Knilans, Michael P.
Carboni, Richard Czosek, and Ronald J. Kanter PART 7: SYNCOPE, SUDDEN DEATH, AND CARDIOPULMONARY RESUSCITATION 48. Diagnosis and Management of Syncope, Mark D. Carlson and Blair P. Grubb 49. Sudden Cardiac Death, Matthew R. Reynolds, Amit J. Thosani, Duane S.
Pinto, and Mark E. Josephson 50. Cardiopulmonary and Cardiocerebral Resuscitation, Jooby John and Gordon A. Ewy PART 8: CORONARY HEART DISEASE 51. Preventive Strategies for Coronary Heart Disease, Michael J. Blaha, Kerunne S. Ketlogetswe, Chiadi E. Mdumele, Ty J.
Gluckman, and Roger S. Blumenthal 52. Atherothrombosis: Disease Burden, Activity, and Vulnerability, Erling Falk and Valentin Fuster 53. Coronary Thrombosis: Local and Systemic Factors, Juan Jose Badimon, Borja Ibanez, Valentin Fuster, and Lina Badimon 54. Coronary Blood Flow and Myocardial Ischemia, Christophe Depre, Stephen F. Vatner, and Garrett J. Gross 55. Nonatherosclerotic Coronary Heart Disease, Bruce F.
Waller 56. Definitions of Acute Coronary Syndromes, Michael C. Kim, Annapoorna S. Kini, and Valentin Fuster 57. Pathology of Myocardial Ischemia, Infarction, Reperfusion, and Sudden Death, Saami K. Yazdani, Elena Ladich, and Renu Virmani 58. Molecular and Cellular Mechanisms of Myocardial Ischemia-Reperfusion Injury, Scott Visovatti, Takanori Hayasaki, Cyril Ruwende, and David J. Pinsky 59.
Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction, James A. de Lemos, Robert A. O''Rourke, and Robert Harrington 60. ST-Segment Elevation Myocardial Infarction, Emily E. Hass, Eric H. Yang, Bernard J. Gersh, and Robert A. O''Rourke 61.
Pharmacologic Therapy for Acute Coronary Syndromes, Dominick J. Angiolillo, Gregory r. Giugliano, and Daniel I. Simon 62. Percutaneous Coronary Intervention, John S. Douglas, Jr, and Spencer B. King, III 63. Mechanical Interventions in Acute Myocardial Infarction, William W.
O''Neill and Pedro Martinez-Clark 64. The Evaluation and Management of Chronic Ischemic Heart Disease, Bradley A. Maron and Patrick T. O''Gara 65. Coronary Bypass Surgery, Joseph F. Sabik, III, Sameer Bansilal, and Bruce W. Lytle 66. Management of the Patient After Cardiac Surgery, Douglas C.
Morris, Stephen D. Clements, Jr., and John Pepper 67. Rehabilitation of the Patient With Coronary Heart Disease, Ian M. Graham, Noeleen Fallon, Shirley Ingram, Tora Leong, John Gormley, Veronica O''Doherty, Vincent Maher, and Suzanne E. Benson PART 9: SYSTEMIC ARTERIAL HYPERTENSION 68. Epidemiology of Hypertension, Gbenga Ogedegbe and Thomas G. Pickering 69.
Pathophysiology of Hypertension, John E. Hall, Joey P. Granger, Daniel W. Jones, and Michael E. Hall 70. Diagnosis and Treatment of Hypertension, G. Brandon Atkins, Mahboob Rahman, and Jackson T. Wright, Jr.
PART 10: CARDIOPULMONARY DISEASE 71. Pulmonary Hypertension, Robyn J. Barst and Lewis J. Rubin 72. Pulmonary Embolism, Peter F. Fedullo 73. Chronic Cor Pulmonale, Marc A. Miller, Joseph M.
Sweeny, E. Clinton Lawrence, and Kenneth L. Brigham 74. Epidemiology and Mechanisms Linking Sleep-Disordered Breathing and Cardiac Disease, Reena Mehra and Susan Redline PART 11: VALVULAR HEART DISEASE 75. Acute Rheumatic Fever, Bongani M. Mayosi and Jonathan R. Carapetis 76. Aortic Valve Disease, Rosario V.
Freeman and Catherine M. Otto 77. Mitral Valve Regurgitation, David H. Adams, Blase A. Carabello, and Javier G. Castillo 78. Mitral Stenosis, Blase A. Carabello 79.
Tricuspid Valve, Pulmonary Valve, and Multivalvular Disease, Pravin M. Shah 80. Prosthetic Heart Valves, Joanna Chikwe, Farzan Filsoufi, and Alain Carpentier 81. Antithrombotic Therapy for Valvular Heart Disease, Usman Baber and Valentin Fuster PART 12: HEART FAILURE.